基因檢測標準品 > Mutation > CBP10215TP53 p.H214R Reference Standard 標準品
名稱
TP53 p.H214R Reference Standard 標準品
型號
CBP10215
報價
特點
TP53 p.H214R Reference Standard
詳細內(nèi)容
CBP10215
Format
Genomic DNA
Description
TP53 H214R lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). H214R results in increased IL-6 expression and colony formation compared to wild-type Tp53 in cell culture (PMID: 11920959), and is therefore predicted to confer a gain of function to Tp53.
Technical Data
DNA Change
c.641A>G
AA Change
p.H214R
Mutation type
Substitution - Missense
Zygosity
Heterozygous
Allelic Frequency
35.47%
Transcript
ENST00000269305
Cosmic ID
COSM43687
Chr position(GRCh37)
chr17:7578208
Buffer
Tris-EDTA
Product Information
Intended Use
Research Use Only
Unit Size
1ug
Concentration
Download for COA
Purofication
Download for COA
DNA electrophoresis
Download for COA
Sanger sequencing
Storage
4℃
Expiry
36 months from the date of manufacture
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