| 名稱 | CDH1 p.PENEKG164del Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10449 |
| 報價 |  |
| 特點(diǎn) | CDH1 p.PENEKG164del Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10449CDH1 p.PENEKG164del Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10449 | |
| Gene | CDH1 |
| Description | CDH1, cadherin 1, type 1, encodes E-Cadherin and is a tumor suppressor (PMID: 30562755) involved in epithelial cell-cell adhesion, cell signaling, differentiation, and polarity (PMID: 18726070, PMID: 26674224). CDH1 germline mutations are associated with hereditary diffuse gastric cancer (PMID: 30562755) and somatic mutations are found in gastric, breast, colon, and NSCLC cancers (PMID: 27283171, PMID: 25184143). |
| Technical Data | |
| DNA Change | c.493_510del |
| AA Change | p.PENEKG164del |
| Mutation type | In_Frame_Del |
| Zygosity | Homozygous |
| Allelic Frequency | 100.00% |
| Transcript | ENST00000261769.5 |
| Cosmic ID | COSM13114 |
| Chr position(GRCh37) | chr16:68842432_68842449 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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