| 名稱 | PDL1/MHCII APC Cell |
| 型號 | CBP74147 |
| 報價 |  |
| 特點 | PDL1/MHCII APC Cell 凍存條件：90% FBS+10% DMSO |
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- 詳細內容
| CBP74147 | |
| I. Background | |
| The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T-cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. The PD-1 ligands are found on most cancers, and PD-1:PD-L1/2 interaction inhibits T cell activity and allows cancer cells to escape immune surveillance. diabetes. | |
| II. Introduction | |
| Expressed gene: | PD1、LAG3 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin+10ug/ml blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional(Report Gene) Assay |
| III. Representative Data | |
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Figure 1. Dose Response of Blocking Antibodies in PD-1/LAG3 Dual Effector Reporter Cells (C15) With PD-L1/MHCII APC Cells. | |
